Journal: Nature Communications
Article Title: Development and validation of self-monitoring auto-updating prognostic models of survival for hospitalized COVID-19 patients
doi: 10.1038/s41467-022-34646-2
Figure Lengend Snippet: a ROC and PR curves with AUC and 95% CI for the retrospective ( n = 1889) and prospective ( n = 25,677; no updates) validation cohorts, b calibration plots for the retrospective validation cohort, c calibration plots for the prospective (no updates) validation cohort and d decision curves for the retrospective and prospective (no updates) cohorts based on the original NOCOS, logistic regression, and XGBoost models. The blue dots on the calibration plots show the actual proportion of outcomes averaged over deciles of the predicted probabilities. The red histograms show the counts of patients that survived past 28 days binned by the predicted probabilities. The green histograms show the counts of patients that died before 28 days binned by the predicted probabilities. The diagonal black lines indicate perfect calibration. The ICIs along with their 95% CIs are reported. ROC receiver operating characteristic, PR precision recall, AUC area under the ROC or PR curve, CI confidence interval, ICI integrated calibration index.
Article Snippet: Three different model types—generalized linear model with the least absolute shrinkage and selection operator (LASSO) penalization (the Northwell COVID-19 Survival Calculator (NOCOS)) , logistic regression (LR) with LASSO penalization , and extreme gradient boosted decision tree (XGBoost) —were trained on patients from the development cohort for 28-day survival.
Techniques: